![]() Unlike many police dramas of the day that featured dark, grim or dismal street scenes, Miami Vice showed almost exclusively bright, vibrant and colorful settings. Detectives Sonny Crockett and Rico Tubbs, played by Don Johnson and Philip Michael Thomas, wore expensive, pastel colored suits and drove around in Ferraris and speedboats, with Miami a constant backdrop. ![]() The stunning cinematography of the show was primarily shot in the South Beach neighborhood of Miami and featured creative camera angles, intriguing action shots and stunning images of everything from vintage deco buildings to boats, prisons, tropical islands and more. The driver of the boat wasn’t shown, but we see brief snippets of expensive cars, bikini clad women, fit jai alai players, flamingos, parrots and beach front high rises, all of which implored viewers to imagine that they were on that speed boat and experiencing all of those things through the eyes of the boat driver.īright colors, beauty, fast living, luxury and wealth are explicitly implied to intrigue those watching. The Keep reminds us a lot of David Fincher’s Alien3. The theme music was upbeat and rhythmic as we watched a speed boat zip through the waters of Miami. Find out where Miami Vice is streaming, if Miami Vice is on Netflix, and get news and updates, on Decider. 242 Likes, 34 Comments - SkateBird Miami (skatebird305) on Instagram: 'Hey I’m Isaiah Aka Peanut I’ve been skating for over 12 years Growing up in Glenmont Maryl. ![]() ![]() Stylistically, Miami Vice was also unique and in a way, ahead of its time. ![]()
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![]() ![]() Good quality vinyl flooring is an easy stylish flooring option for home areas, such as kitchens, entrance areas, and dry bathroom, as they come in a wide variety of textures and designs for the trendiest home interior looks. Vinyl sheet and vinyl tiles are recommended for these applications. Vinyl flooring is also appropriate for stylish commercial properties that benefit from water-resistant features, such as restaurants and cafes. Commercially graded vinyl flooring can be applied to properties with heavy duty traffic, such as car factory, showrooms, and other industrial settings. Some vinyl flooring are embedded with anti-static properties, making them suitable to be used for sterile environments, laboratories, as well as hospitals. High quality vinyl flooring can be applied in various commercial flooring areas. More questions on what is vinyl flooring? Feel free to get in touch with our flooring team HERE. We help to break down the differences between vinyl flooring and resilient flooring here. As vinyl flooring comes under the resilient flooring umbrella, vinyl flooring providers may label them as a form of resilient flooring by using terms such as high end, luxury, among others. Usually installed with patented Unilin or Valinge glueless click system, clickable vinyl planks are naturally waterproof, and they act as a good choice of flooring for residential kitchens or dry bathroom areas. Often installed in high human traffic areas, such as industrial areas, the vinyl flooring is able to withstand heavy traffic from moving machinery and vehicles. The most common ones from flooring providers would be natural-looking wood inspired designs, granite, or marble designs. Vinyl tiles usually come in squarish shapes, and have a wide variety of flooring patterns. ![]() New to this flooring innovation and want to find out what is vinyl flooring? Here are three main types of vinyl flooring you can obtain in Singapore. Applicable to both commercial properties as well as residential homes, it has received positive reception for its high durability and flexible properties, when compared to traditional homogenous tiles. Vinyl flooring is undeniably one of the most common types of flooring in the industry. ![]() ![]() ![]() You could call that jumping the gun, but that's what passionate fans will get you - as a result, anyone trying to look into the subject needs to sort through *checks notes* almost a decade of speculation, hoaxes, threads, posts, articles, captions and more to find out what they want to know. Until any greater volume of official news regarding the franchise's future is publicized, this will be your one-stop resource for anything GTA 6-related.įans have been thinking and talking about GTA 6 for many years now, as hype around the game has been building practically since GTA 5 launched. In this GTA 6 overview, we'll look at everything we know, everything we think we know, and all the rumors worth noting. While situations change - like Benzies departing from Rockstar - we know that the company went ahead with the continuation of the franchise. In an interview, Leslie Benzies (president of Rockstar North at the time) indicated that the team already had ideas for the next game. Technically, GTA 6 was sort of 'confirmed' way back in 2013, the release year of GTA 5. If we look at past release trends from Rockstar and Take-Two, we can make some educated guesses, discussed below. At this point, little is clear beyond the fact that it's probably going to launch sometime during the current PlayStation 5 / Xbox Series X|S console generation. But you just need to bookmark this page to find out the official release date of Grand Theft Auto as soon as it gets announced.Being the popular topic of speculation that it is, Grand Theft Auto 6 is also the subject of many rumors and hoaxes. All the leaks and our speculations can be accurate or slightly off from the actual release date, which is yet to be announced by Rockstar Games. With that, you now know everything about the GTA VI release date. Though, only time would tell if their estimate is as reliable as we expect. Keep in mind that Microsoft is the owner of two major platforms (Xbox & Windows) for the GTA franchise, so it wouldn’t be surprising that they have insider knowledge about a major title’s release timeline. While doing so, a statement in the same section mentions that “The highly anticipated Grand Theft Auto VI is expected to be released in 2024,”. They brought up the success of Take-Two Interactive and others to clarify that Microsoft’s takeover of Activision won’t affect the competition. In a recent response to the UK Competition and Markets Authority (CMA) investigation of Microsoft’s acquisition of Activision Blizzard, the company mentioned the release window of GTA 6. So, our fingers are crossed, but if things do go haywire, then GTA 6 might get delayed to late 2025. Even though leaks hype up the game among the players, they can also end up delaying their release by a good few months or a year or two.Īs of writing this piece, the story is still developing with the leaker threatening developers with a bigger GTA VI source code leak. This huge GTA 6 leak is highly devastating to the game developer and investors. On September 18th, 2022, a leaker posted 90+ videos and lines from the source code of GTA 6. Potential GTA 6 Release Delay by Massive Leak But again, there is no way to know if that event can lead to a specific release date or just an unrelated announcement. One of the most important Tuesdays of 2024 is the 22nd anniversary of GTA Vice City. ![]() Moreover, as reported in our overall GTA 6 guide, the game is supposedly based on Vice City. There is no reason to break the pattern with GTA 6 as well. Since the release of GTA Vice City, every GTA title has been released on a Tuesday. But, please keep in mind that we are merely speculating the date, and there is no official announcement yet. With both these leaks and the previous release dates in mind, we expect GTA 6 to release in October or November of 2024. Back in March, Klippel claimed that GTA 6 won’t release before the last months of 2024. This was later backed by Bloomberg reporter Jason Schreier in a separate Twitter thread, who expects a release date of late 2024 or early 2025. Keeping that in mind, we expect to witness the release of GTA 6 in the final months of the upcoming years.Īt the moment, the most reliable idea of GTA VI’s release date we have is from Chris Klippel, a popular GTA leaker. Leaving that aside, we have four titles in the last two weeks of October and three in November. The only exception is GTA 4, which was released in April 2008. GTA: The Trilogy – The Definitive EditionĪs you might notice, Rockstar Games have released all its major games in the Fall months of each year. To get a realistic idea of GTA 6’s release date, let’s go over the release dates of other major gaming titles by Rockstar Games. Microsoft Expects GTA 6 Release in 2024.Potential GTA 6 Release Delay by Massive Leak. ![]() ![]() We found constitutive association between D2DR, VEGFR-2 and SHP-2. Whole-cell lysates from serum-starved HUVECs were immunoprecipitated with D2DR antibody and immunoblotted with antibodies against VEGFR-2 and SHP-2. Therefore, we performed coprecipitation experiments to identify specific protein tyrosine phosphatases that are involved in the dopamine-mediated VEGFR-2 dephosphorylation. ResultsĪs dopamine modulates VEGFR-2 tyrosine phosphorylation, we posited that certain phosphatases might be involved in this modulation. Here, we examine how dopamine specifically regulates one of the earliest steps of the angiogenic process, the VEGF-induced phosphorylation of VEGFR-2, and define a novel role of Src-homology-2-domain-containing protein tyrosine phosphatase 2 (SHP-2) in the dopamine-mediated anti-angiogenic pathway. Although it is known that dopamine can inhibit different signaling steps involved in VEGF-mediated angiogenesis, beginning at VEGFR-2 phosphorylation ( Basu et al., 2001 Bhattacharya et al., 2008b Sarkar et al., 2004), the pathophysiological implication of dopamine in the context of VEGF-induced angiogenesis is novel and requires further investigation. Dopamine, when applied to patients with septic shock, can effectively maintain the circulatory stability and promote restoration of renal function ( Dellinger et al., 2008). Dopamine has a role in the management of Parkinson's disease and is also involved in the etiopathogenesis of several neuropsychiatric diseases such as schizophrenia ( Egan and Weinberger, 1997 Goldstein and Deutch, 1992 Graybiel et al., 1990 Olanow and Tatton, 1999). Dopamine is produced in a wide variety of animals including both vertebrates and invertebrates, and activates the five types of dopamine receptors – D1, D2, D3, D4 and D5 – and their variants ( Neve et al., 2004). ![]() The role of the neurotransmitter dopamine in modulating VEGF-induced angiogenesis has been well defined ( Basu et al., 2001 Sarkar et al., 2004). The binding of VEGF to its receptors induces dimerization and subsequent receptor phosphorylation, which then leads to the activation of several intracellular downstream signaling pathways promoting angiogenesis ( Olsson et al., 2006 Sakurai et al., 2005 Takahashi et al., 2001 Zachary, 2003). VEGFR-2, the major positive signal transducer for both physiological and pathological angiogenesis ( Mukhopadhyay et al., 2004 Shibuya, 2006), is selectively expressed on vascular endothelial cells. The VEGF receptor family consists of three members, namely VEGFR-1, VEGFR-2 and VEGFR-3 ( Shibuya, 2008). As one of the most important cytokines, VEGF is widely expressed by a number of human and animal tumors and has the ability to regulate most of the steps in the angiogenic signal cascade ( Dvorak, 1990 Dvorak et al., 1999 Dvorak et al., 1979 Ferrara, 1999 Risau, 1997). Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF), is an important mediator of these angiogenic processes in both normal and diseased conditions. Our data establish a novel role for SHP-2 phosphatase in the dopamine-mediated regulation of VEGFR-2 phosphorylation.Īngiogenesis performs a crucial role in physiological conditions, including embryonic development, wound healing and organ regeneration, as well as in pathological processes such as diabetes retinopathies, atherosclerosis, tumorigenesis and tumor metastasis ( Carmeliet, 2003 Ferrara et al., 2003 Folkman, 1971 Folkman, 1995 Sueishi et al., 1997). We also observe that SHP-2 knockdown impairs the dopamine-regulated inhibition of VEGF-induced phosphorylation of VEGFR-2 and, subsequently, Src phosphorylation and migration. Active SHP-2 then dephosphorylates VEGFR-2 at Y951, Y996 and Y1059, but not Y1175. Dopamine administration leads to increased VEGF-induced phosphorylation of SHP-2 and this increased phosphorylation parallels the increased phosphatase activity of SHP-2. Dopamine pretreatment increases the translocation and colocalization of Src-homology-2-domain-containing protein tyrosine phosphatase (SHP-2) with D2DR at the cell surface. Here, we demonstrate that D2 dopamine receptor (D2DR) colocalizes with VEGFR-2 at the cell surface. ![]() ![]() In this study, we address the mechanism by which VEGFR-2 phosphorylation is regulated by dopamine. Our previous studies have shown that the neurotransmitter dopamine could inhibit VEGF-induced phosphorylation of VEGF receptor 2 (VEGFR-2), endothelial cell proliferation, migration, microvascular permeability, and thus, angiogenesis. Vascular endothelial growth factor (VEGF)-induced receptor phosphorylation is the crucial step for initiating downstream signaling pathways that lead to angiogenesis or related pathophysiological outcomes. ![]() ![]() ![]() What started as an idea to revive a dying drive-in movie theater evolved into a massive international chain of hundreds of adult theaters and bookstores. Go next door for some real one on one fun. Deja Vu Showgirls website Founded over 50 years ago, Deja Vu® has modest Midwestern roots in the adult theater business. Marshals announced today that the suspect, Cordell Jones. VIP rooms with massive jacuzzi rubs and rooms for you to get the crap beaten out of you if that's your thing. A 'Michigans Most Wanted' fugitive tied to a fatal shooting at the Déjà Vu nightclub in Highland Park has been arrested. Plenty of room with something like 8 stages. Since the insane grand opening in 1984, the Ypsi Vu’ has lit up the cool Michigan skies with some of the most sizzling stage strutters in the state. 16 reviews of Deja Vu Showgirls 'I have been down in T.J.working on the new Deja Vu. The club boasts four VIP rooms, 14 couches, and a splash of fantasy booths. YPSILANTI, MI The Déjà Vu Showgirls strip club is suing the city of Ypsilanti and the city’s planning commission claiming its rights are being violated through intentional bureaucratic work. ![]() ![]() With a swollen customer capacity of just over 150, the Ypsi locale whacks em and stacks em with over 30 lusty and lovely nude entertainers served up on one main stage. Located in downtown Ypsilanti is the petite Déjà Vu of Ypsilanti. So large numbers of students in Ann Arbor have relocated to Ypsilanti thus creating a vibrant underground arts scene, bohemian cultural center and some of the hottest women in the country. A 'Michigan's Most Wanted' fugitive tied to a fatal shooting at the Dj Vu nightclub in Highland Park has been arrested. Comparable to the gentrification causing many artist’s, poets, musicians and hipsters to flee the Lower East Side of Manhattan. It has been said that Ypsilanti is the Brooklyn to Ann Arbor’s Manhattan. Eastern Michigan University is located here, with several other colleges that are within the semi immediate area including the University of Michigan. Deja Vu Showgirls Strip Club was closed to the public at the time of. Ypsilanti, Michigan is roughly six miles east of Ann Arbor, Michigan and connects easily to downtown Detroit via interstates. KALAMAZOO, MI A person was arrested Monday afternoon after they allegedly crashed a truck into a Kalamazoo strip club. ![]() ![]() ![]() There is a tendency to underestimate the amount of work that goes into an electronic watch, Arnault explains, but he wants to double down on investment and expand the brand’s resources. The beauty of Vuitton, he adds, is that it can focus on the high craftsmanship of both the mechanical and electronic aspects of making smartwatches. However, unlike the independent brands or indeed Zenith, Vuitton has invested “significant resources” in the development of its own connected smartwatch, the Tambour Horizon, which he says is half of the business. Very roughly, this equates to around 25,000 pieces per annum. And he describes the core business in mechanical timepieces, up to around €12,000 per watch, as being similar to the size of LVMH stablemate Zenith. He likens his high watchmaking business to that of fellow Swiss independent brands such as FP Journe and De Bethune. LVMH, overall, reported higher-than-expected revenue of €18.4bn for the second quarter of this year - but the world’s biggest luxury group does not disclose figures for its individual luxury brands - let alone product sectors within brands. ![]() Vuitton’s watches can be found only in the brand’s 200 own boutiques, with online sales accounting for “low two figures in terms of percentage”. Initially, markets told us we would be able to sell three, now we have orders for 30.” “We’re surprised by the number of traditional collectors we recruited through that piece. “Some people say that the GPHG award is not worth much commercially, but it made a huge impact, both commercially and in terms of reputation,” he observes. Arnault is marking his first year at the helm of the brand’s watch division, having notched up two wins at the GPHG in that time - one for best diving watch and the audacity prize for its half-million-euro Carpe Diem timepiece. However, this month sees another anniversary chez Vuitton, which has already brought awards. The new model has been entered into this year’s Grand Prix d’Horlogerie de Genève (GPHG) - the Oscars of the watch world. ![]() It is a 200-piece limited edition chronograph, equipped with a modified El Primero calibre from Zenith, also part of the LVMH watch stable. The brand’s signature watch design has been the Tambour - a bulbous, drum-like case shape which has been central to Vuitton’s development, and the anniversary is being marked with the Tambour Twenty. ![]() ![]() ![]() ![]() No, I got into acting due to my old man being a minister. So did you get into acting through being Santa Claus? There were some real adventures in that, but I just kind of got tired of doing it, especially just being away from my wife’s family on Christmas Eve for 30 years. I actually kind of quit doing Santa Claus on personal levels because for years and years I would deliver presents on Christmas Eve to different households. Well, I wouldn’t say I still do, but that’s where it started. So you have sort of like an emotional attachment to playing the character of Santa Claus? And I’m saying, “why aren’t they giving these kids toothbrushes and things they need?” That just kind of started me going honestly. So I would see these kids, they would come up and sit on my lap, a lot of them missing teeth, and we’re giving out things like candy. ![]() At that time, it was the old gaslamp - now it’s thriving with all kinds of new bars and stuff, but back then it was skid row. It was a real eye-opener to me about what a difference Santa Claus could make in somebody’s life. They had a booth set up after the parade was over to bring people up and sit on Santa’s lap and stuff. First gig I got hired for was down in San Diego for their Christmas parade. So when I got to be old enough, I said, well, I want to see what Santa Claus is like. Santa and Satan are pretty much the same dude. So we didn’t have Santa when we were growing up. This is your third or fourth time playing Santa Claus, isn’t it? How did that come about? Did this kind of grow out of that? I’ve got a costume fitting this afternoon and I’m working next week. When it’s good, it’s very good, and when it’s bad, it sucks. One of them is about 30 pounds and the other one’s about 10, 11, 12, something like that. They’re mutts I got from the pound, rescue dogs, little terriers. We’ve been here probably close to 30 years. Fodder for ITYSL season three, I hope? I spoke to Wiff via Zoom this week. When it’s bad, it sucks.”) He’s also in the rare position of being able to compare The Santa Claus Circuit in different cities. He currently lives in LA with his wife and two dogs, and he lives a life typical, in many ways, of any struggling actor. He declined to share his birth name (“Everybody calls me Biff except my mom, my doctors, and the police”). Wiff says it came from his time in a song parody troupe called The Piparoos. Wiff had a face that positively screamed “this guy’s got some stories,” and in speaking to him for what turned out to be his first interview with any media, I discovered that my instincts had not been wrong. He seems to specialize in crusty outsiders, with other credits that include “Homeless Man” ( Homecoming, Desperate Housewives), “Cart Driver” ( Westworld), and “Hollywood Hobo” ( iCarly). I Think You Should Leave is actually Wiff’s third credited role as Santa Claus, after 9-1-1 and Just Roll With It. Naturally, I wanted to know more about this man. Netflixĭid I mention the actor’s name is “Biff Wiff?” I crack up every time I think about some of his line reads. It’s the verisimilitude of him looking like a real mall Santa mixed with the surprise of him effortlessly handling these jarring tone shifts that becomes something sublime. He combines a face that looks like it’s lived some hard years with a voice that sounds like Droopy Dog’s beer drunk uncle, with a soupçon of stoned surf dude. It’s reminiscent both of inarticulate action stars not quite committing to their roles, and of that “extra gear” many actors have in press tour interviews, where they can slip into flowery pretension without warning.Ī big part of the reason it all works is the actor playing Santa Claus. I won’t say anyone else’s list is right or wrong, but for me the sketch that instantly stood out as the most memorable was “Detective Crashmore.” It’s a sketch that reimagines Santa Claus - which is to say the actual, mythical Santa Claus, who gives gifts and judges when children have been good or bad - as an aging movie star promoting a reactionary detective series.Īt the risk of explaining a joke, the beauty of the sketch is that it’s strange and surreal, but also an incisive parody - a quality that probably a lot of great I Think You Should Leave sketches have, of being simultaneously far-fetched and applicable. Everyone probably has their favorite sketch from I Think You Should Leave season two. ![]() ![]() ![]() ![]() buffer function that consumes the entry by buffering the contents into memory and returning a promise to the complete buffer. While the recommended strategy of consuming the unzipped contents is using streams, it is sometimes convenient to be able to get the full buffered contents of each file. pipe(fs.createWriteStream('firstFile.txt')) Buffering the content of an entry into memory If no file matches then the the stream will end without any content.Įxample: fs.createReadStream('path/to/archive.zip') The unzipper package is an NPM package created as a replacement for the unzip package to address some of the package’s notable shortcomings, including its synchronous nature, unreliable triggering of open/close events, and a high memory footprint. Otherwise, each filename will be compared to the criteria and the first one to match will be unzipped and piped down. If no search criteria is specified, the first file in the archive will be unzipped. Unzipper.parseOne() is a convenience method that unzips only one file from the archive and pipes the contents down (not the entry itself). pipe(unzipper.Extract()) Parse a single file and pipe contents Installation $ npm install nextpoint-unzipper Quick Examples Extract to a directory fs.createReadStream('path/to/archive.zip') The Open methods will check for crx headers and parse crx files, but only if you provide crx: true in options. crx file with the streaming methods ( Parse and ParseOne). Please note: Methods that use the Central Directory instead of parsing entire file can be found under OpenĬhrome extension files (.crx) are zipfiles with an extra header at the start of the file. There are no added compiled dependencies - inflation is handled by node.js's built in zlib support. Unzipper provides simple APIs similar to node-tar for parsing and extracting zip files. Speeds up unzipping password protected zips by updating crc hashing using BigInt with minimal conversions between numbers and BigInts.Fixes unzipping from central directory (with unzipper.Open method) by fixing errors that occurred at ~40 entries to allow unzipping an entire zip file with this method.pipe(unzipper.Extract()) Ĭonst type = entry.type // 'Directory' or 'File'Ĭonst size = is an active fork of node-unzipper and addresses the following issues: Quick Examples Extract to a directory fs.createReadStream('path/to/archive.zip') The new Parser will push any parsed entries downstream if you pipe from it, while still supporting the legacy entry event as well.īreaking changes: The new Parser will not automatically drain entries if there are no listeners or pipes in place. The structure of this fork is similar to the original, but uses Promises and inherit guarantees provided by node streams to ensure low memory footprint and emits finish/close events at the end of processing. Any files are buffered into memory before passing on to entry.finish/close events are not always triggered, particular when the input stream is slower than the receivers.This is an active fork and drop-in replacement of the node-unzip and addresses the following issues: ![]() ![]() ![]() Research on GT has also become more diverse in terms of themes, with finance, Covid-19 and other health-related topics being the new dominant areas of research. Overall, the results show that the research on Google Trends has grown considerably in recent years, particularly since the outbreak of the Covid-19 pandemic. In the paper, two types of analyses are carried out: 1) a citation-based analysis that focuses on the overall publication trends and the identification of the most prolific authors, documents, journals, and countries, and 2) a mapping of themes in GT research and how these have evolved. We extracted bibliometric data from the Scopus database which were then analyzed quantitatively using the Bibliometrix software package. In this study, we conducted a bibliometric study of the first 15 years of Google Trends research (2007–2022). Since its introduction in 2006, it has been widely used in research in a variety of academic fields. Google Trends is a free analytic tool for measuring and monitoring web search data. Our study will provide various insights for researchers who utilize Google Trends as well as researchers who rely on various other sources of Big Data in their efforts to compare research trends and identify new areas for research. This study also demonstrates that in recent years, there has been an expansion in analysis in linkage with other social Big Data sources, as researchers attempt to overcome the limitations of using only search information. In addition, this study shows that research using Google Trends has increased dramatically in the last decade, and in the process, the focus of research has shifted to forecasting changes, whereas in the past the focus had been on merely describing and diagnosing research trends, such as surveillance and monitoring. ![]() The study reveals that Google Trends is used to analyze various variables in a wide range of areas, including IT, communications, medicine, health, business and economics. We also identified the important nodes of the networks and reviewed the research directions of representative papers. To this end, we conducted a network analysis on 657 research papers that used Google Trends. Our purpose is to conduct a comprehensive and objective research into how the public use of Big Data from web searches has affected research, and furthermore, to discuss the implications of Google Trends in terms of Big Data utilization and application. This study seeks to analyze the trends in research studies in the past decade which have utilized Google Trends, a new source of big data, to examine how the scope of research has expanded. ![]() ![]() ![]() To help you remember, take it at the same time(s) each day. Use this medication regularly to get the most benefit from it. Swallow the whole tablet without crushing or chewing. Doing so can release all of the drug at once, increasing the risk of side effects. ![]() If you are taking capsules, swallow each capsule whole.ĭo not crush or chew extended-release tablets. If you are taking the chewable form of this medication, chew thoroughly before swallowing. Do not use a household spoon because you may not get the correct dose. If you are using the liquid form of this medication, carefully measure the dose using a special measuring device/spoon. If you have any questions, ask your doctor or pharmacist. For best absorption, if your total daily dose is more than 600 milligrams, then divide your dose and space it throughout the day. Follow all directions on the product package, or take as directed by your doctor. ![]() If your product contains calcium citrate, then it may be taken with or without food. Having the right amounts of vitamin D, calcium, and phosphorus is important for building and keeping strong bones. Vitamin D helps your body absorb calcium and phosphorus. If there is not enough calcium in the blood, then the body will take calcium from bones, thereby weakening bones. It is necessary for normal functioning of nerves, cells, muscle, and bone. It may also be used in certain patients to make sure they are getting enough calcium (including women who are pregnant, nursing, or postmenopausal, people taking certain medications such as phenytoin, phenobarbital, or prednisone).Calcium plays a very important role in the body. It may be used to treat conditions caused by low calcium levels such as bone loss ( osteoporosis), weak bones ( osteomalacia/ rickets), decreased activity of the parathyroid gland ( hypoparathyroidism), and a certain muscle disease (latent tetany). This combination medication is used to prevent or treat low blood calcium levels in people who do not get enough calcium from their diets. ![]() |